Tag Archives: Kidney Transplant in Delhi


Treatment of Chronic Renal Failure

The chronic renal failure (CRF) is a disease characterized by the progressive deterioration of renal function which results in the kidney loses the ability to make urine, and in turn to remove toxins from the blood, among other functions they are necessary for life.

Treatment of Chronic Renal Failure

A patient is considered to have Chronic Renal Insufficiency when he has a glomerular filtration rate lower than 60ml / min / 1.73m2, resulting from structural or functional abnormalities of the kidney, for at least three months.

Among the kidney’s own functions that are altered in renal failure are:

  • The acid-base and electrolyte balance, necessary to maintain the pH and the amount of water and salts that the body needs (sodium, potassium, and phosphorus)
  • Elimination of toxins.
  • Endocrine functions, such as the production of erythropoietin necessary for the production of red blood cells, and avoid anemia.
  • Regulation of calcium metabolism (essential for the proper function of bones)

These are some of the substances that accumulate in blood product of cell metabolism and that in the case of suffering from renal failure are not eliminated properly, and can be harmful when they accumulate in the blood:

  • Urea
  • Creatinine
  • Ureic Nitrogen in Blood (BUN)
  • Sodium (present in salt): Favors the retention of liquids
  • Potassium (present in fruits, vegetables, and nuts): as a serious consequence among others can produce an irreversible cardiac arrest.
  • Phosphorus (present in bread, dairy, and pastries): In excess produces itching and contributes to vascular calcification.
  • Excesses of water (come mainly from drinks and meals): Increases blood pressure, and can lead to acute pulmonary edema, which is a serious condition, where the lung cannot exercise its function to oxygenate the blood because occupied by liquid.

Causes of the CRF

Causes that can cause Chronic Renal Insufficiency:

  • Infections of either the urinary, kidney or systemic pathways that affect the kidney (for example pyelonephritis)
  • Medications that affect the kidney (for example chronic interstitial nephritis, caused mostly by non-steroidal anti-inflammatory drugs, such as ibuprofen and diclofenac and some antibiotics, among other medicines)
  • Injuries, tumors
  • Acquired or hereditary renal diseases (for example, glomerulonephritis or polycystic kidney disease in more than 20%)
  • Diabetes mellitus (more than 20%)
  • Hypertension
  • Atherosclerosis (fatty deposits, as cholesterol, inside the arteries, in more than 15%)
  • Systemic hereditary diseases with kidney involvement
  • Urinary tract stones

Symptoms of CRF

The symptoms of advanced chronic renal failure (CRF) are mainly associated with the retention of urea and electrolytes such as phosphorus and potassium, and fluid retention, with edema in the legs (swollen legs) and shortness of breath (edema) in lung; also when the levels of urea are very high the following signs and symptoms may appear:

  • Tiredness
  • Nausea
  • Vomiting
  • Loss of appetite
  • Weight loss
  • Headache
  • Insomnia
  • Numbness or muscle pain in arms and/or legs
  • Spiked
  • Blurred vision
  • Heart problems
  • Anemia and malnutrition
  • Edema in the eyelids and legs (fluid retention)
  • Osteodystrophy (decalcification and fragility of the bones)
  • Stomach discomfort (gastritis)

Treatments: hemodialysis and peritoneal dialysis

Techniques of renal replacement therapy: Hemodialysis or Peritoneal Dialysis

Among the techniques of renal replacement therapy, that is to say, those that will supply kidney function, when they present a significant deterioration of between 5-15% of their capacity, it is necessary to choose the technique depending on the characteristics of the patient and the recommendations of your nephrologist in Delhi.

In both cases, once the treatment is started, both hemodialysis and peritoneal dialysis recover the feeling of well-being and improve the functioning of the body’s systems.

Kidney Transplant

Kidney transplant in Delhi is the best renal replacement therapy because it offers the possibility of a better quality of life by restoring all affected functions and eliminates the need for chronic dialysis in Delhi. A transplanted kidney can work well for many years, depending on the general health of the recipient and the characteristics of the donor’s kidney.

In any case, before being a candidate for a kidney transplant recipient, additional tests should be performed to ensure optimal performance, since it requires immunosuppressive drugs, that is, they depress the body’s natural defenses and predispose other diseases of an infectious nature, as well as the success of surgery, since it does not stop being a surgical intervention with its risks. So not all patients are suitable for such intervention, should be assessed by a nephrologist in Delhi and the transplant team.


Acute Kidney Disease Treatment by Best Nephrologist in Delhi


According to Best Nephrologist in Delhi Dr. Vinant Bhargava, an acute renal disease is basically a problem that lots of people have wherein the kidney does not separate waste from blood likewise it could. The kidney is a vital organ who performs many functions in our body, however, first and foremost it cleans waste material like potassium and calcium and roots it out from our body through urine. Many individuals suffer from acute kidney disease earlier than other people. Hypertension and diabetic issues are the most known problems that trigger individuals to develop acute kidney disease. Sadly, lots of people who are suffering from acute kidney disease also suffer from arthritis or chronic pain.

Various drugs are separated out of the body system by the kidneys. It indicates that once you develop acute kidney disease, few drugs are taken in a different way or perhaps disallowed completely. Drugs as essential as antibiotics could require kidney functionality adaptation, so it is extremely vital to consult with your doctor and understand your kidney functionality.

Acute kidney disease can furthermore lead to transitions in the human body, including anemia or bone disorder. The kidneys exude a hormone which induces bone marrow to generate blood cells. If the hormone is not exuded properly, anemia may possible to develop. The kidneys additionally support the human body to utilize calcium and vitamin D effectively. in absence of the complete functionality of the kidneys, individuals can suffer from a bone disease, like osteoporosis.

Well, presented all of these facts, what a person can do to avoid acute kidney disease? By far and away the most crucial thing a person can do is regulate blood sugar and pressure. Blood pressure should be checked often and diet should be built as recommended by a dietician.

The more salt, the steeper the blood pressure. High sugar also damages the kidney. If you are suffering from obesity, or have a family background of diabetes, it’s important to have blood sugar checked.

If acute kidney disease does not treat well it may lead to total failure of the kidney and then a person needs to go for a kidney transplant. For kidney transplant in Delhi, many patients visit Dr. Vinant Bhargava and his expert surgeon team.

Kidney Transplant in Delhi

Kidney Transplant

Kidney Transplant in Delhi

Kidney transplant in Delhi consists of the extraction of a kidney from a previously healthy individual (cadaver or live) and its placement in a patient with chronic end-stage renal failure and incompatible with life. A kidney transplant surgeon in Delhi performs the operation. Technically, the operation is simple and consists of three anastomosis or joints (arterial, venous and urinary). The duration of the intervention in the recipient is about 3-4 hours. It allows the integral recovery of renal function and normal life. It requires the taking of anti-rejection or immunosuppressive medication for life and frequent medical checks from a kidney transplant doctor in Delhi.

Kidney Transplant in Delhi

Depending on the origin of the graft, it can be a living relative donor (parents, siblings, children, cousins), an emotionally related living donor (for example, between spouses) and a cadaver donor (due to previous brain death or standing heart). The best results are obtained with a live donor kidney transplant.

When is it indicated?

In all patients with end-stage chronic renal failure and without contraindications, prior to the start of dialysis or once included in hemodialysis or peritoneal dialysis program. It requires the performance of a series of analytical, immunological studies, various imaging techniques, assessment of cardiac, pulmonary, neurological, urological, etc., being subsequently included in the waiting list for kidney transplantation in the transplant unit of your area of influence.

What are the results?

At present, the results of renal corpse transplantation are very good, achieving a graft survival of around 90% per year, 70-75% at five years and 50-60% at 10 years. The main causes of long-term graft loss are chronic rejection and death of a patient with a functioning graft in relation to cardiovascular problems, infections, tumors, and liver disease. The results of renal transplantation of living donors are higher than those of cadavers and are characterized by a lower incidence of acute rejection and superior results in terms of graft survival that can be 98% per year, after five years of 85% and at 10 years of 75%.

What advantages does it offer?

The main one is that it restores or normalizes all kidney functions, including the production of erythropoietin-like hormones (necessary for the production of red blood cells), vitamin D (for normal bone maintenance), etc., and not just the function of uropoiesis or elimination of water and waste products such as urea, creatinine, potassium, phosphorus, etc. … that perform the different peritoneal dialysis or hemodialysis techniques.

It also allows a better physical and psychic state, a better quality of life and is the cheapest therapeutic option from the year with a functioning graft.

What are the complications?

The most frequent early complications are those related to surgery (urinary obstruction, urinary fistula, liquid collections, surgical wound infection, urinary tract infections, lung infections, etc.). The incidence of high blood pressure, an increase in uric acid, increase in cholesterol is high. In the longer term, the main complications are infections, malignant tumors, chronic rejection, and cardiovascular complications.

Who can be transplanted?

Not all patients with terminal chronic renal failure can be transplanted due to problems or limitations of a medical or surgical nature. This is the case of patients older than 70-75 years (valuing biological age rather than chronological age) and those with significant problems of cardiac, hepatic, neurological, pulmonary origin, chronic
infectious pathology, unresolved tumor diseases, etc. Any patient in whom the vital risk of the operation and of the complications associated with the anti-rejection medication is considered excessive or important, it is better to contraindicate the kidney transplant in Delhi.

What is the waiting list?

Once all the relevant studies have been carried out and it has been verified by the doctor for kidney transplant in Delhi that the patient meets all the requirements and indications for renal transplantation, the data is sent to the reference hospital where the renal transplant unit is located and from where the patient will be notified (through the kidney transplant doctor in Delhi responsible for its follow-up) as soon as a suitable kidney is available due to its characteristics.

Among the necessary data are age, dialysis unit, blood group, tissue typing, cytotoxic antibody results, type of nephropathy, hemodialysis program start date, location telephones, etc. … and the results of the various pre-transplant studies. In India, it can only be included in a waiting list for kidney transplantation.

What is expected of the receiver?

  • To take the medication correctly with the dose and interval indicated by the nephrologist in Delhi responsible for its follow-up.
  • That blood pressure, weight, and temperature be monitored periodically.
  • That you consult quickly before episodes of fever, edema, decrease in urine output or any other complication related or not with kidney transplantation.

It is also important to perform daily physical activity, eat a proper diet, avoid tobacco, maintain the ideal weight, etc.

What is the anti-rejection treatment?

It consists of taking immunosuppressive medication to avoid rejection and achieve graft tolerance. There are various immunosuppression protocols depending on age, degree of immunological risk, depending on whether they are first or more grafts, etc, suggests nephrologist in Delhi.

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